vacuous

everything and nothing points to one thing

67 notes

jaebean asked: As an aquarius, do you feel like sometimes you don't know what the hell you're feeling?

aquariussitsalone:

Yes…I tend to feel multiple or even all of the emotions simultaneously and I have no idea what to do so I just stand there staring off into space like a crazy person…frozen by all of the feelings….like what are they doing in my body? What do they want from me?? WHY ARE THEY MAKING MY SKIN AND BLOOD CHANGE TEMPERATURE LIKE WHAT. WHAT DO YOU WANT, FEELINGS?! HMMMM???!!!!

74 notes

neurosciencestuff:

Division of labour in the fish brain
For a fish to swim forward, the nerve cells, or neurons, in its brain and spine have to control the swishing movements of its tail with very close coordination. However, the posture of the tail, which determines swimming direction somewhat like a rudder, also needs to be fine-tuned by the brain’s activity. Using the innovative method of optogenetics, scientists from the Max Planck Institute of Neurobiology in Martinsried have now identified a group of only about 15 nerve cells which steer the movements of the tail fin. Movements of the human body are also controlled via nerve pathways in the same region of the brain, which may therefore use processing mechanisms similar to those in fish.
For a long time, neurobiologists have been trying to find out how neuronal networks control both animal and human behaviour. In this context, there is controversy as to whether the brain’s organisation is decentralised as opposed to modular. In decentralised organisation, the interaction of a large number of neurons produces a specific behaviour pattern. If this is the case, individual neurons cannot be assigned an exact function. On the other hand, if the brain has a modular structure, individual regions might possess certain competencies, each making a specific contribution to behaviour. These types of neuronal circuit modules could be combined in many ways and influence a broad range of different behavioural responses.
Switches in the fish brain?
Researchers in Herwig Baier’s Group at the Max Planck Institute of Neurobiology want to get to the bottom of the brain’s organisational structure with the aid of zebrafish larvae. A network known as the descending reticular formation is located in the brainstem of these animals. The neurons of that region are optimally suited for studying the organisation of the brain: the cells are in direct contact with motor neurons in the spinal cord of the fish and can thus directly influence tail movements. “The reticular formation is a like a ‘cockpit’ for the fish, and we asked ourselves whether there are individual ‘switches’ or ‘joysticks‘, which are used to control the movements of the tail”, is how Herwig Baier summarises this challenge.
In their search for these switches, the researchers concentrated on a small brain nucleus (nMLF) within the reticular formation. But how can the influence of individual nMLF neurons on tail movements be studied? It is only recently that such investigations even became a possibility. Using the new method of optogenetics, the activity of nerve cells can be influenced with light. Since a zebrafish larva – including its brain – is transparent, scientists can very accurately “switch on” small sets of genetically modified cells by exposing the larva to blue light. Consequently, tail movements that are induced in this way can be attributed to identified neurons.
Neurons and tillers
The first series of tests showed that the cells of the nMLF region seem to be involved in a variety of movements – from forward propulsion to rotational motion. A second experimental series using optogenetic stimulation, however, suggested that the cells control the deflection of the tail in particular. Are the nMLF cells thus part of a multifunctional centre or are they truly specialised to perform certain functions? To resolve this question, the neurobiologists performed another set of trials in which they very specifically removed small sets of nMLF cells from the circuit. “This experiment gave us our breakthrough”, recalls Tod Thiele, lead author of the now published study.
The results show that, while nMLF cells are active in many aspects of swimming, a subset of these neurons contribute to only one part of the movement: they determine swimming direction through the posture of the tail. Thus, this population of neurons in the nMLF region are more akin to a specialised module within a decentralised control system of the swimming apparatus. Herwig Baier explains it like this: “We can compare the whole setup with the propulsion of a motorboat”. The boat’s engine, which drives the propeller, determines the thrust, whereas the tiller steers the boat. It seems that the tasks in the brain are divided up in a very similar way.
Some time ago, Herwig Baier’s team discovered a small region in the hindbrain, which acts like an engine and propels the fish forwards. “With the nMLF cells, we have now also found the tiller in the fish brain”, says Herwig Baier. In the human brain, movements are also controlled by a multitude of nuclei in the reticular formation. The study therefore suggests that the allocation of tasks in our brain could be similar to that of the zebrafish.

neurosciencestuff:

Division of labour in the fish brain

For a fish to swim forward, the nerve cells, or neurons, in its brain and spine have to control the swishing movements of its tail with very close coordination. However, the posture of the tail, which determines swimming direction somewhat like a rudder, also needs to be fine-tuned by the brain’s activity. Using the innovative method of optogenetics, scientists from the Max Planck Institute of Neurobiology in Martinsried have now identified a group of only about 15 nerve cells which steer the movements of the tail fin. Movements of the human body are also controlled via nerve pathways in the same region of the brain, which may therefore use processing mechanisms similar to those in fish.

For a long time, neurobiologists have been trying to find out how neuronal networks control both animal and human behaviour. In this context, there is controversy as to whether the brain’s organisation is decentralised as opposed to modular. In decentralised organisation, the interaction of a large number of neurons produces a specific behaviour pattern. If this is the case, individual neurons cannot be assigned an exact function. On the other hand, if the brain has a modular structure, individual regions might possess certain competencies, each making a specific contribution to behaviour. These types of neuronal circuit modules could be combined in many ways and influence a broad range of different behavioural responses.

Switches in the fish brain?

Researchers in Herwig Baier’s Group at the Max Planck Institute of Neurobiology want to get to the bottom of the brain’s organisational structure with the aid of zebrafish larvae. A network known as the descending reticular formation is located in the brainstem of these animals. The neurons of that region are optimally suited for studying the organisation of the brain: the cells are in direct contact with motor neurons in the spinal cord of the fish and can thus directly influence tail movements. “The reticular formation is a like a ‘cockpit’ for the fish, and we asked ourselves whether there are individual ‘switches’ or ‘joysticks‘, which are used to control the movements of the tail”, is how Herwig Baier summarises this challenge.

In their search for these switches, the researchers concentrated on a small brain nucleus (nMLF) within the reticular formation. But how can the influence of individual nMLF neurons on tail movements be studied? It is only recently that such investigations even became a possibility. Using the new method of optogenetics, the activity of nerve cells can be influenced with light. Since a zebrafish larva – including its brain – is transparent, scientists can very accurately “switch on” small sets of genetically modified cells by exposing the larva to blue light. Consequently, tail movements that are induced in this way can be attributed to identified neurons.

Neurons and tillers

The first series of tests showed that the cells of the nMLF region seem to be involved in a variety of movements – from forward propulsion to rotational motion. A second experimental series using optogenetic stimulation, however, suggested that the cells control the deflection of the tail in particular. Are the nMLF cells thus part of a multifunctional centre or are they truly specialised to perform certain functions? To resolve this question, the neurobiologists performed another set of trials in which they very specifically removed small sets of nMLF cells from the circuit. “This experiment gave us our breakthrough”, recalls Tod Thiele, lead author of the now published study.

The results show that, while nMLF cells are active in many aspects of swimming, a subset of these neurons contribute to only one part of the movement: they determine swimming direction through the posture of the tail. Thus, this population of neurons in the nMLF region are more akin to a specialised module within a decentralised control system of the swimming apparatus. Herwig Baier explains it like this: “We can compare the whole setup with the propulsion of a motorboat”. The boat’s engine, which drives the propeller, determines the thrust, whereas the tiller steers the boat. It seems that the tasks in the brain are divided up in a very similar way.

Some time ago, Herwig Baier’s team discovered a small region in the hindbrain, which acts like an engine and propels the fish forwards. “With the nMLF cells, we have now also found the tiller in the fish brain”, says Herwig Baier. In the human brain, movements are also controlled by a multitude of nuclei in the reticular formation. The study therefore suggests that the allocation of tasks in our brain could be similar to that of the zebrafish.

4 notes

klavieren:

Through our Almighty God’s love and mercy, His Holy Church has reached Her centennial - yes, 100 years of endless love and blessings to the #IglesiaNiCristo! Happy #INC100 #INCCentennial to all the brethren (Mga Kapatid worldwide)! To our brothers and sisters at the #PhilippineArena in #CiudadDeVictoria — You are blessed to witness this historical event, though we are not with you physically: WE [ Members of the true #ChurchOfChrist ] are united through the #LoveOfTheBrotherhood, abounding in #Faith, #Hope, and #Love. We shall be praying for you, our brethren, in our local house of worship, watching you through the live stream via satellite. ❤️🇮🇹💯 “Ako’y Iglesia Ni Cristo” with voices united thanking our Father in heaven for His unfailing love - 100 years of blessings from our God Almighty! #ItsTHECentennial 🙌

klavieren:

Through our Almighty God’s love and mercy, His Holy Church has reached Her centennial - yes, 100 years of endless love and blessings to the #IglesiaNiCristo! Happy #INC100 #INCCentennial to all the brethren (Mga Kapatid worldwide)! To our brothers and sisters at the #PhilippineArena in #CiudadDeVictoria — You are blessed to witness this historical event, though we are not with you physically: WE [ Members of the true #ChurchOfChrist ] are united through the #LoveOfTheBrotherhood, abounding in #Faith, #Hope, and #Love. We shall be praying for you, our brethren, in our local house of worship, watching you through the live stream via satellite. ❤️🇮🇹💯 “Ako’y Iglesia Ni Cristo” with voices united thanking our Father in heaven for His unfailing love - 100 years of blessings from our God Almighty! #ItsTHECentennial 🙌

2 notes

"what is---?" 5 min. writing prompt; "what is, 100 years?"

what is 100 years?

how does it feel,

most of us will never know.

100 seconds feels like eternity

when you’re waiting for the red light.

or for the patrol with his baynonet

waiting, hiding, waiting for him to just pass by.

100 days feels like 100 nights

when your home was swallowed by the…

It is the Centennial.
My name is melissa
I am a member of the Church of Christ

And I want to invite you
To share the joy it has given my life

Incmedia.org

Filed under inc100

2 notes

describe a moment

melnomore:

when the glory of the moment

basks in stifled tears

through singing the words of the song

the story of the years

all emotion grasped in this moment

overjoyed, humbled

in the oneness

through the tone

a hymn psalmed by His own

in that moment, they know

He is here. Listening. Their heartsong

he heard them. 

they have reached home.

Today this is now

Filed under inc100

0 notes

This is the type of crap that so many of you pull. You overstep your boundaries and consider that YOUR emotional attachment to someone, no matter how twisted, is more important than another person’s autonomy and personal agency. No one wants to hang out with someone or let alone be in the same vicinity with a leech.
talkingtodeadguys

Filed under freeyourselves